1, [b](Re)Grinding[/b] - Think a big reason why many players don't enjoy grinding anymore is because the game loop has been very stale & predictable for years on end from a macro perspective - if the game doesn't considerably update itself on a semi-regular basis, people get bored/tired of the same old same old and move onto the new freshness somewhere else...
2, [b]Serving the Audience/Quality of Content/Management[/b] - Reality is, Destiny doesn't cater it's audience, it has previously tried to extract the most from the least possible resources, relying on gimmicks and cheap burn content on average - seasons/episodes are at a very poor quality and the team isn't agile enough to shift development at a fast enough pace due to poor management, institutional bloat and a of lack of overarching vision. I like Tyson Green and think their vision for the game is what's been needed for a long time, If this can be executed and at a pace that can retain/grow players remains to be seen.
3, [b]PR & Trust[/b] - As much as I like Destiny 2 for some things, Bungie has destroyed a significant part of their own fanbase. Goodwill and trust is sorely lacking, to the point many want to see Bungie fail due to the volume of their mistakes & perceived arrogance - Bungie is not a likeable company, as much as some might think this doesn't matter, it often has a large impact on overall game sales and marketing.
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My biggest gripe is the constant targeted nerfs that kill builds. This has just ruined build crafting for me because why bother making a build knowing it’s just gonna get nuked. The prismatic fragment controversy is a prime example. Plus Lately it’s just been more nerfs than buffs in patch notes. Power fantasy is fun it’s what drew myself and many others to the game. Bungie keeps trying to remove that and it just ruins the most important aspect of gaming called FUN.